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S100A16 蛋白

S100A16 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319484
发货至: 中国
  • 抗原 See all S100A16 蛋白
    S100A16 (S100 Calcium Binding Protein A16 (S100A16))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 1
    • 1
    资源
    • 5
    • 1
    • 1
    大肠杆菌(E. Coli)
    原理
    Recombinant Human S100A16/S100F Protein
    序列
    Met1-Ser103
    产品特性
    Recombinant Human S100A16 is produced by our E.coli expression system and the target gene encoding Met1-Ser103 is expressed.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product S100A16 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 500 mM NaCl, pH 8.0.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    S100A16 (S100 Calcium Binding Protein A16 (S100A16))
    别名
    S100A16/S100F (S100A16 产品)
    别名
    DT1P1A7 Protein, S100F Protein, 2300002L21Rik Protein, AI325039 Protein, AI663996 Protein, S100 calcium binding protein A16 Protein, S100A16 Protein, S100a16 Protein
    背景

    Background: S100A16 is a member of S100 protein superfamily that carries calcium-binding EF-handmotifs. S100 proteins are cell-and tissue-specific and are involved in many intra-and extracellular processes hrough interacting with specific target proteins. S100A16 expression was found to be astrocyte-specific. The S100A16 protein was found to accumulate within nucleoli and to translocate to the cytoplasm in response to Ca(2+) stimulation. The homodimeric structure of human S100A16 in the apo state has been obtained both in the solid state and insolution, resulting in good agreement between the structures with the exception of two loop regions. The homodimeric solution structure of human S100A16 was also calculated in the calcium(II)-bound form. Immunoprecipitation analysis revealed that S100A16 could physically interact with tumor suppress or protein p53, also a known inhibitor of adipogenesis. Overexpression or RNA interference-initiated reduction of S100A16 led to the inhibition or activation of the expression of p53-responsivegenes, respectively. S100A16 protein is a novel adipogenesis-promoting factor.

    Synonym: SLAM Family Member 6, Activating NK Receptor, NK-T-B-Antigen, NTB-A, CD352, SLAMF6, KALI, Ly108, NTBA, SF2000

    分子量
    11.8 kDa
    UniProt
    Q96FQ6
    途径
    S100 Proteins
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