S100A16 Protein (AA 1-103)
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北京 101111
Quick Overview for S100A16 Protein (AA 1-103) (ABIN7319484)
抗原
See all S100A16 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 1-103
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原理
- Recombinant Human S100A16/S100F Protein
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序列
- Met1-Ser103
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产品特性
- Recombinant Human S100A16 is produced by our E.coli expression system and the target gene encoding Met1-Ser103 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 116,946.14 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 145,985.55 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 20 mM Histidine-HCl, 6 % Trehalose, 4 % Mannitol, 100 mM NaCl, 0.05 % Tween 80, pH 5.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- S100A16 (S100 Calcium Binding Protein A16 (S100A16))
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别名
- S100A16/S100F
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背景
- Activating NK Receptor,CD352,KALI,Ly108,NK-T-B-Antigen,NTB-A,NTBA,SF2000,SLAM Family Member 6,SLAMF6,S100A16 is a member of S100 protein superfamily that carries calcium-binding EF-handmotifs. S100 proteins are cell-and tissue-specific and are involved in many intra-and extracellular processes hrough interacting with specific target proteins. S100A16 expression was found to be astrocyte-specific. The S100A16 protein was found to accumulate within nucleoli and to translocate to the cytoplasm in response to Ca(2+) stimulation. The homodimeric structure of human S100A16 in the apo state has been obtained both in the solid state and insolution, resulting in good agreement between the structures with the exception of two loop regions. The homodimeric solution structure of human S100A16 was also calculated in the calcium(II)-bound form. Immunoprecipitation analysis revealed that S100A16 could physically interact with tumor suppress or protein p53, also a known inhibitor of adipogenesis. Overexpression or RNA interference-initiated reduction of S100A16 led to the inhibition or activation of the expression of p53-responsivegenes, respectively. S100A16 protein is a novel adipogenesis-promoting factor.
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分子量
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Calculated MW: 11.8 kDa
Observed MW: 12 kDa
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基因ID
- 140576
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UniProt
- Q96FQ6
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途径
- S100 Proteins
抗原
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