S100A1 蛋白
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北京 101111
Quick Overview for S100A1 蛋白 (ABIN7197741)
抗原
See all S100A1 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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原理
- Recombinant Human S100A1 Protein
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序列
- Met 1-Ser 94
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产品特性
- A DNA sequence encoding the human S100A1 (NP_006262.1) (Met 1-Ser 94) was expressed.
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过滤
- 0.2 μm filtered
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Biological Activity Comment
- Immobilized recombinant human Fc-S100B at 10 μg/mL (100 μl/well) can bind biotinylated human S100A1 with a linear range of 15.6-250 ng/mL. 3. Measured by its ability to bind human His-S100B in functional ELISA.
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S100 Calcium Binding Protein A1 (S100A1) (AA 1-94) protein (His tag)
S100A1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
S100 Calcium Binding Protein A1 (S100A1) (AA 1-94) protein (His-IF2DI Tag)S100A1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
S100 Calcium Binding Protein A1 (S100A1) (AA 1-94) protein (His-IF2DI Tag)S100A1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
S100 Calcium Binding Protein A1 (S100A1) (AA 1-94) protein (GST tag)S100A1 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- S100A1 (S100 Calcium Binding Protein A1 (S100A1))
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别名
- S100A1
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背景
- S100,S100-alpha,S100A,S100A1 is a Ca2+binding protein of the EF-hand type that belongs to the S100 protein family. S100 proteins consisting of at least 19 members exist as dimers in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation.This protein has been shown to function in the processes including stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of PKC-mediated phosphorylation.. Phosphoglucomutase is a target protein whose activity is antagonistically regulated by S100A1, and recently, S100A1 is also identified as a potent molecular chaperone and a new member of the Hsp70/Hsp90 multichaperone complex. S100A1 displays a tissue-specific expression pattern with highest levels in myocardium and is considered to be an important regulator of cardiac contractility. Accordingly, reduced expression or mutations of S100A1 gene have been implicated in cardiomyopathies.
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分子量
- 10.5 kDa
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基因ID
- 6271
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NCBI登录号
- NP_006262
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UniProt
- P23297
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途径
- Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins
抗原
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