Resistin Protein (RETN) (AA 19-108) (His tag)
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Quick Overview for Resistin Protein (RETN) (AA 19-108) (His tag) (ABIN7319264)
抗原
See all Resistin (RETN) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 19-108
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标记
- This Resistin protein is labelled with His tag.
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原理
- Recombinant Human Resistin Protein (His Tag)
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序列
- Lys19-Pro108
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产品特性
- Recombinant Human Adipose tissue-specific secretory factor is produced by our E.coli expression system and the target gene encoding Lys19-Pro108 is expressed with a 6His tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 20 mM HAc, pH 3.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Resistin (RETN)
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别名
- Resistin
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背景
- ADSF,Adipose tissue-specific secretory factor,C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein,Cysteine-rich secreted protein A12-alpha-like 2,Cysteine-rich secreted protein FIZZ3,FIZZ3,HXCP1,RETN,RETN1,RSTN,Resistin,XCP1,Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. The length of the resistin pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa, the molecular weight is ~12.5 kDa. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus (T2DM). Resistin has been shown to cause "high levels of 'bad' cholesterol (low-density lipoprotein or LDL), increasing the risk of heart disease, resistin increases the production of LDL in human liver cells and also degrades LDL receptors in the liver. Potentially links obesity to diabetes.
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分子量
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Calculated MW: 10.6 kDa
Observed MW: 10-14 kDa
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NCBI登录号
- NP_065148
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途径
- Feeding Behaviour, Smooth Muscle Cell Migration
抗原
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