PTK6 Protein (AA 1-451) (His-GST)
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Quick Overview for PTK6 Protein (AA 1-451) (His-GST) (ABIN7320007)
抗原
See all PTK6 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 1-451
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标记
- This PTK6 protein is labelled with His-GST.
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原理
- Recombinant Mouse PTK6/Brk Protein (His & GST Tag)
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序列
- Met1-Val451
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产品特性
- A DNA sequence encoding the mouse PTK6 (Q64434) (Met1-Val451) was expressed with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- The specific activity was determined to be 5 nmol/min/mg using poly [Glu, Tyr] 4:1 as substrate.
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想要此Protein的其他选项吗？
!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Mouse价格从 116,946.14 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Mouse价格从 145,985.55 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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PTK6 Protein tyrosine Kinase 6 (PTK6) (AA 1-451) protein (His tag)
custom-made PTK6 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
PTK6 Protein tyrosine Kinase 6 (PTK6) (AA 1-451) protein (His tag)custom-made PTK6 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
PTK6 Protein tyrosine Kinase 6 (PTK6) protein (GST tag)PTK6 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 89 % as determined by reducing SDS-PAGE.
PTK6 Protein tyrosine Kinase 6 (PTK6) (AA 1-451) protein (GST tag)PTK6 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
PTK6 Protein tyrosine Kinase 6 (PTK6) (Active) protein (Myc-DYKDDDDK Tag)PTK6 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, PI, STD Active
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))
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别名
- PTK6/Brk
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背景
- BRK,Sik,Tksk,tks,Tyrosine kinase (PTKs) is a protein that carry out tyrosine phosphorylation, which play a fundamental role in cell proliferation, survival, adhesion, and motility and have also been demenstrated to mediate malignant cell transformation. Overexpression of this protein in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Two classes of PTKs are present in cells: the transmembrane receptor PTKs and the non-receptor PTKs. Tyrosine kinase(PTKs)-6/ BRK is a cytoplasmic non-receptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Tyrosine kinase(PTKs)-6/ BRK has been shown to undergo autophosphorylation. It has been found that the constitutive expression of the tyrosine kinase(PTKs)-6/ BRK is in a large proportion of cutaneous T-cell lymphomas and other transformed T- and B-cell populations. State BRK expression was also induced in normal T-cells. In clinical, the cytoplasmic tyrosine kinase PTK6 (BRK) shows elevated expression in approximately two-thirds of primary breast tumours, and is implicated in EGF receptor-dependent signalling and epithelial tumorigenesis.
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分子量
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Calculated MW: 79.8 kDa
Observed MW: 66 kDa
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UniProt
- Q64434
抗原
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