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Proteoglycan 3 Protein (PRG3) (His tag)

PRG3 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318966
发货至: 中国
  • 抗原 See all Proteoglycan 3 (PRG3) 蛋白
    Proteoglycan 3 (PRG3)
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    资源
    • 2
    • 1
    • 1
    人细胞
    标记
    This Proteoglycan 3 protein is labelled with His tag.
    原理
    Recombinant Human Proteoglycan 3/PRG3 Protein (His Tag)
    序列
    Leu18-Phe225
    产品特性
    Recombinant Human Proteoglycan 3 is produced by our Mammalian expression system and the target gene encoding Leu18-Phe225 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Proteoglycan 3 (PRG3)
    别名
    Proteoglycan 3/PRG3 (PRG3 产品)
    别名
    MBP2 Protein, MBPH Protein, proteoglycan 3, pro eosinophil major basic protein 2 Protein, proteoglycan 3 Protein, PRG3 Protein, Prg3 Protein
    背景

    Background: Proteoglycan 3, also known as Eosinophil major basic protein homolog, Prepro-major basic protein homolog, PRG3 and MBPH, contains one C-type lectin domain. Proteoglycans are a major component of the animal extracellular matrix. PRG3 localizes to the eosinophil secondary granule and is expressed in bone marrow, not detected in placenta. PRG3 has similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, PRG3 can stimulate neutrophil superoxide production and IL8 release, histamine and leukotriene C4 release from basophils.

    Synonym: Proteoglycan 3, Eosinophil Major Basic Protein Homolog, Prepro-Major Basic Protein Homolog, Prepro-MBPH, PRG3, MBPH

    分子量
    24.6 kDa
    UniProt
    Q9Y2Y8
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