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PKD2 Protein (His-GST)

This Recombinant PKD2 protein is expressed in Baculovirus infected Insect Cells.
产品编号 ABIN7317066
发货至: 中国
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Quick Overview for PKD2 Protein (His-GST) (ABIN7317066)

抗原

See all PKD2 蛋白
PKD2 (Protein Kinase D2 (PKD2))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 12
  • 2

资源

  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Baculovirus infected Insect Cells

纯度

> 82 % as determined by reducing SDS-PAGE.
  • 标记

    This PKD2 protein is labelled with His-GST.

    原理

    Recombinant Human PRKD2/PKD2 Protein (His & GST Tag)

    序列

    Met 1-Leu 878

    产品特性

    A DNA sequence encoding the amino acid sequence (Met 1-Leu 878) of human PRKD2 (NP_057541.2) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    The specific activity was determined to be > 30 nmol/min/mg using synthetic CREBtide peptide (KRREILSRRPSYR) as substrate.
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 145,985.55 ¥

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  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied as sterile solution of 50 mM Tris, 500 mM NaCl, 0.5 mM PMSF, 10 % glycerol, pH 8.0

    储存液

    PMSF

    储存条件

    -20 °C

    储存方法

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    PKD2 (Protein Kinase D2 (PKD2))

    别名

    PRKD2/PKD2

    背景

    HSPC187,PKD2,nPKC-D2,Serine/threonine-protein kinase D2, also known as PRKD2 and PKD2, is a cytoplasm and membrane protein which belongs to theprotein kinase superfamily, CAMK Ser/Thr protein kinase family and PKD subfamily. PRKD2 / PKD2 is widely expressed. It contains onePH domain, twophorbol-ester/DAG-type zinc fingers and oneprotein kinase domain. PRKD2 / PKD2 is activated by DAG and phorbol esters. Phorbol-ester/DAG-type domains bind DAG, mediating translocation to membranes. Autophosphorylation of Ser-710 and phosphorylation of Ser-706 by PKC relieves auto-inhibition by the PH domain. PRKD2 / PKD2 converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress.

    分子量

    Calculated MW: 124 kDa

    Observed MW: 120 kDa

    基因ID

    25865

    NCBI登录号

    NP_057541

    UniProt

    Q9BZL6

    途径

    cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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