PRCP Protein (His tag)
Quick Overview for PRCP Protein (His tag) (ABIN7318751)
抗原
See all PRCP 蛋白蛋白类型
宿主
资源
纯度
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标记
- This PRCP protein is labelled with His tag.
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原理
- Recombinant Human PRCP Protein (His Tag)
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序列
- Leu22-His496
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产品特性
- Recombinant Human Lysosomal Pro-X Carboxypeptidase is produced by our Mammalian expression system and the target gene encoding Leu22-His496 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM NaAc-HAc,150 mM NaCl,10 % Glycerol, pH 4.5.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- PRCP (Prolylcarboxypeptidase (PRCP))
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别名
- PRCP
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背景
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Background: Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH , but enzymatic activity is retained with some substrates at neutral pH . PRCP has been shown to be an activator of the cell matrix-associated prekallikrein.
Synonym: Lysosomal Pro-X Carboxypeptidase, Angiotensinase C, Lysosomal Carboxypeptidase C, Proline Carboxypeptidase, Prolylcarboxypeptidase, PRCP, PRCP, PCP
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分子量
- 54.5 kDa
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UniProt
- P42785
抗原
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