Prolactin Protein (PRL) (AA 29-227) (His tag)
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北京 101111
Quick Overview for Prolactin Protein (PRL) (AA 29-227) (His tag) (ABIN7318933)
抗原
See all Prolactin (PRL) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 29-227
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标记
- This Prolactin protein is labelled with His tag.
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原理
- Recombinant Human Prolactin/PRL Protein (His Tag)
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序列
- Leu29-Cys227
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产品特性
- Recombinant Human Prolactin is produced by our Mammalian expression system and the target gene encoding Leu29-Cys227 is expressed with a 6His tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Prolactin (PRL) protein (His tag)
PRL 宿主: 绵羊 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Prolactin (PRL) (Active) proteinPRL 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Prolactin (PRL) (AA 30-226) protein (His-IF2DI Tag)PRL 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Prolactin (PRL) (AA 30-226) protein (His-IF2DI Tag)PRL 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Prolactin (PRL) (AA 29-227) protein (Fc Tag)PRL 宿主: 人 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Prolactin (PRL) protein (His tag)PRL 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 92 % as determined by reducing SDS-PAGE.
Prolactin (PRL) (AA 29-227) protein (GST tag)PRL 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
Prolactin (PRL) (AA 29-227) protein (Fc Tag,AVI tag,Biotin)PRL 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 % Trehalose, 5 % Mannitol, 0.01 % Tween 80, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Prolactin (PRL)
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别名
- Prolactin/PRL
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背景
- PRL,Prolactin,Prolactin (PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation, but has pleiotropic effects in both males and females. Non-glycosylated prolactin is produced by the pituitary and packaged in storage granules before secretion, while glycosylated prolactin is reported to be constitutively secreted, have lower biological potency, and be removed from the circulation more quickly. Prolactin is synthesized mainly by the anterior pituitary in all mammals, where secretion is under tonic inhibition by hypothalamic dopamine. In humans, prolactin is also produced peripherally. Prolactin expression is low during early human pregnancy, but increases in late pregnancy. The prolactin receptor (PRLR) is a transmembrane type I glycoprotein that belongs to the cytokine hematopoietic receptor family. prolactin molecule is thought to bind two receptor molecules. In addition to its lactogenic activity, peripherally produced prolactin plays roles in breast and prostate cancer development, regulation of reproductive function, and immunoregulation.
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分子量
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Calculated MW: 23.9 kDa
Observed MW: 25-30 kDa
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基因ID
- 5617
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UniProt
- P01236
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途径
- JAK/STAT Signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Protein targeting to Nucleus
抗原
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