Prokineticin 1 Protein (Prok1) (His tag)
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Quick Overview for Prokineticin 1 Protein (Prok1) (His tag) (ABIN7318098)
抗原
See all Prokineticin 1 (Prok1) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Prokineticin 1 protein is labelled with His tag.
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原理
- Recombinant Human EG-VEGF/prokineticin-1 Protein (His Tag)
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序列
- Met 1-Phe105
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产品特性
- A DNA sequence encoding the human EG-VEGF (Met 1-Phe105) (P58294) was expressed, with a C-terminal polyhistidine tag.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 0.02 % Tween 80, 10 % glycerol, 1 mM DTT.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存液
- Dithiothreitol (DTT)
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注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Prokineticin 1 (Prok1)
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别名
- EG-VEGF/prokineticin-1
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背景
- EGVEGF,PK1,PRK1,EG-VEGF, also known as prokineticin-1, is a member of the AVIT (prokineticin) family. Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. EG-VEGF can be detected in the steroidogenic glands, ovary, testis, adrenal and placenta. EG-VEGF has little or no effect on a variety of other endothelial and non-endothelial cell types. It induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. EG-VEGF may play a role in placentation. It may also function in normal and pathological testis angiogenesis. It positively regulates PTGS2 expression and prostaglandin synthesis.
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分子量
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Calculated MW: 11 kDa
Observed MW: 15 kDa
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基因ID
- 84432
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UniProt
- P58294
抗原
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