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Quick Overview for CD31 蛋白 (ABIN7197410)
抗原
See all CD31 (PECAM1) 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human CD31/PECAM1 Protein
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序列
- Met 1-Lys 601
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产品特性
- The mature form of human CD31 (EAW94208.1) extracellular domain (Met1-Lys 601) with five additional amino acids (DDDDK) at the C-terminus was expressed and purified.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 28-602) (Active) protein (His tag)
PECAM1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 28-601) (Active) protein (His tag)PECAM1 宿主: 人 宿主: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. WB, SDS, Imm, ELISA, AcA Active
Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 28-150) protein (His tag)PECAM1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 1-738) protein (GST tag)PECAM1 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 29-738) protein (GST tag)PECAM1 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 18-590) protein (His tag)PECAM1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile 100 mM Glycine, 10 mM NaCl, 50 mM Tris, pH 7.5
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
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别名
- CD31/PECAM1
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背景
- CD31;EndoCAM;GPIIA;PECA1;PECAM-1;PECAM1 ;Platelet endothelial cell adhesion molecule,The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.
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分子量
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Calculated MW: 65.1 kDa
Observed MW: 115 kDa
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基因ID
- 5175
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UniProt
- P16284
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途径
- Regulation of Actin Filament Polymerization
抗原
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