PHYH Protein (AA 31-338)
This Recombinant PHYH protein is expressed in 大肠杆菌（E. Coli）.
产品编号 ABIN7317253
发货至:
中国
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Quick Overview for PHYH Protein (AA 31-338) (ABIN7317253)
抗原
See all PHYH 蛋白
PHYH
(Phytanoyl-CoA 2-Hydroxylase (PHYH))
蛋白类型
Recombinant
宿主
人
资源
大肠杆菌（E. Coli）
纯度
> 80 % as determined by reducing SDS-PAGE.
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产品特性
- AA 31-338
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原理
- Recombinant Human PHYH Protein
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序列
- Ser31-Leu338
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产品特性
- A DNA sequence encoding the human PHYH (O14832) (Ser31-Leu338) was expressed, with a N-terminal Met.
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过滤
- 0.2 μm filtered
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Biological Activity Comment
- Not validated for activity
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Phytanoyl-CoA 2-Hydroxylase (PHYH) (AA 1-338) protein (GST tag)
PHYH 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Phytanoyl-CoA 2-Hydroxylase (PHYH) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PHYH 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile 20 mM mops, 10 % glycerol, 2 mM DDT, 1 mM EDTA, 0.2 mM PMSF, 0.2M NaCl, pH 7.2
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存液
- PMSF
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- PHYH (Phytanoyl-CoA 2-Hydroxylase (PHYH))
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别名
- PHYH
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背景
- LN1,LNAP1,PAHX,PHYH1,RD,PHYH belongs to the family of iron(II)-dependent oxygenases, which typically incorporate one atom of dioxygen into the substrate and one atom into the succinate carboxylate group. PHYH is expressed in liver, kidney, and T-cells, but not in spleen, brain, heart, lung and skeletal muscle. It converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Defects in PHYH can cause Refsum disease (RD). RD is an autosomal recessive disorder characterized clinically by a tetrad of abnormalities: retinitis pigmentosa, peripheral neuropathy, cerebellar ataxia, and elevated protein levels in the cerebrospinal fluid (CSF). Patients exhibit accumulation of the branched-chain fatty acid, phytanic acid, in blood and tissues.
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分子量
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Calculated MW: 35.6 kDa
Observed MW: 26-32 kDa
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基因ID
- 5264
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UniProt
- O14832
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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