PMM2 Protein (His tag)
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北京 101111
Quick Overview for PMM2 Protein (His tag) (ABIN7318900)
抗原
See all PMM2 蛋白蛋白类型
宿主
资源
纯度
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标记
- This PMM2 protein is labelled with His tag.
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原理
- Recombinant Human PMM2 Protein (His Tag)
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序列
- Met 1-Ser246
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产品特性
- Recombinant Human Phosphomannomutase 2 is produced by our E.coli expression system and the target gene encoding Met1-Ser246 is expressed with a 6His tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Phosphomannomutase 2 (PMM2) (AA 1-242) protein (His tag)
custom-made PMM2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Phosphomannomutase 2 (PMM2) (AA 1-246) protein (GST tag)PMM2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Phosphomannomutase 2 (PMM2) protein (Myc-DYKDDDDK Tag)PMM2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- PMM2 (Phosphomannomutase 2 (PMM2))
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别名
- PMM2
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背景
- PMM 2,PMM2,Phosphomannomutase 2,Phosphomannomutase 2 (PMM2) is an enzyme that is a member of the highly variable methyltransferase superfamily. PMM2 is a cytoplasmic protein and catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate.In addition, PMM2 involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose that required for a number of critical mannosyl transfer reactions. Defects in PMM2 can results in congenital disorder of glycosylation type 1A (CDG1A). Congenital disorders of glycosylation are metabolic deficiencies in glycoprotein biosynthesis that usually cause severe mental and psychomotor retardation.
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分子量
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Calculated MW: 29.1 kDa
Observed MW: 29 kDa
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基因ID
- 5373
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UniProt
- O15305
抗原
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