PMM1 Protein (His tag)
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北京 101111
Quick Overview for PMM1 Protein (His tag) (ABIN7318899)
抗原
See all PMM1 蛋白蛋白类型
宿主
资源
纯度
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标记
- This PMM1 protein is labelled with His tag.
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原理
- Recombinant Human PMM1 Protein (His Tag)
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序列
- Met 1-Ala262
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产品特性
- Recombinant Human Phosphomannomutase 1 is produced by our E.coli expression system and the target gene encoding Met1-Ala262 is expressed with a 6His tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 1 mM DTT, pH 8.0.
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储存液
- Dithiothreitol (DTT)
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注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- PMM1 (Phosphomannomutase 1 (PMM1))
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别名
- PMM1
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背景
- PMM 1,PMM1,PMMH-22,PMMH22,Phosphomannomutase 1,Phosphomannomutase 1 (PMM1) blongs to the eukaryotic PMM family. Phosphomannomutase 1 can catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose which required for a number of critical mannosyl transfer reactions. PMM1 is highly expressed in liver, heart, brain, and pancreas, but lower expression in skeletal muscle. In addition, PMM1 may be responsible for the degradation of glucose-1,6 bisphosphate in ischemic brain.
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分子量
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Calculated MW: 30.8 kDa
Observed MW: 49 kDa
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基因ID
- 5372
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UniProt
- Q92871
抗原
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