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PMM1 Protein (His tag)

This Recombinant PMM1 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7318899
发货至: 中国
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Quick Overview for PMM1 Protein (His tag) (ABIN7318899)

抗原

See all PMM1 蛋白
PMM1 (Phosphomannomutase 1 (PMM1))

蛋白类型

Recombinant

宿主

人

资源

  • 5
  • 1
  • 1
大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This PMM1 protein is labelled with His tag.

    原理

    Recombinant Human PMM1 Protein (His Tag)

    序列

    Met 1-Ala262

    产品特性

    Recombinant Human Phosphomannomutase 1 is produced by our E.coli expression system and the target gene encoding Met1-Ala262 is expressed with a 6His tag at the C-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 1 mM DTT, pH 8.0.

    储存液

    Dithiothreitol (DTT)

    注意事项

    This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    PMM1 (Phosphomannomutase 1 (PMM1))

    别名

    PMM1

    背景

    PMM 1,PMM1,PMMH-22,PMMH22,Phosphomannomutase 1,Phosphomannomutase 1 (PMM1) blongs to the eukaryotic PMM family. Phosphomannomutase 1 can catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose which required for a number of critical mannosyl transfer reactions. PMM1 is highly expressed in liver, heart, brain, and pancreas, but lower expression in skeletal muscle. In addition, PMM1 may be responsible for the degradation of glucose-1,6 bisphosphate in ischemic brain.

    分子量

    Calculated MW: 30.8 kDa

    Observed MW: 49 kDa

    基因ID

    5372

    UniProt

    Q92871
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