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Persephin Protein (PSPN) (His tag)

PSPN 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319503
发货至: 中国
  • 抗原 See all Persephin (PSPN) 蛋白
    Persephin (PSPN)
    蛋白类型
    Recombinant
    宿主
    • 5
    • 4
    • 1
    资源
    • 7
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This Persephin protein is labelled with His tag.
    原理
    Recombinant Human Persephin/PSPN Protein (His Tag)
    序列
    Ala61-Gly156
    产品特性
    Recombinant Human Persephin is produced by our E.coli expression system and the target gene encoding Ala61-Gly156 is expressed.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PSPN 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Persephin (PSPN)
    别名
    Persephin/PSPN (PSPN 产品)
    别名
    PSPN Protein, PSP Protein, persephin Protein, PSPN Protein, Pspn Protein
    背景

    Background: Persephin is a secreted protein, belongs to the glial cell linederived neurotrophic factor (GDNF) family of the TGF-β superfamily. It shares 38-46 % amino acid (aa) identity with family members GDNF, neurturin and artemin. It is expressed at very low levels in most tissues. Mature protein contains a signal sequence, a pro-domain and a 96 aa mature sequence with several cysteines that are conserved among family members. It circulates as an unglycosylated disulfide-linked homodimer. Like other GDNF family members, Persephin acts through engagement of GRFα4, a glycosylphosphatidylinositol (GPI)-linked GDNF receptor family Persephin is reported to promote both the survival and growth of central dopaminergic and motor neurons, and kidney development. These effects are correlated with the expression patterns of GFRα4, and RET.

    Synonym: Persephin, PSP, PSPN

    分子量
    10.4 kDa
    UniProt
    O60542
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