Persephin Protein (PSPN) (AA 61-156)
This Recombinant Persephin protein is expressed in 大肠杆菌（E. Coli）.
产品编号 ABIN7319503
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for Persephin Protein (PSPN) (AA 61-156) (ABIN7319503)
抗原
See all Persephin (PSPN) 蛋白
Persephin (PSPN)
蛋白类型
Recombinant
宿主
人
资源
大肠杆菌（E. Coli）
纯度
> 95 % as determined by reducing SDS-PAGE.
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产品特性
- AA 61-156
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原理
- Recombinant Human Persephin/PSPN Protein
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序列
- Ala61-Gly156
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产品特性
- Recombinant Human Persephin is produced by our E.coli expression system and the target gene encoding Ala61-Gly156 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Persephin (PSPN) (AA 61-156) protein (His-IF2DI Tag)
PSPN 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Persephin (PSPN)
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别名
- Persephin/PSPN
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背景
- PSP,PSPN,Persephin,Persephin is a secreted protein, belongs to the glial cell linederived neurotrophic factor (GDNF) family of the TGF-β superfamily. It shares 38-46 % amino acid (aa) identity with family members GDNF, neurturin and artemin. It is expressed at very low levels in most tissues. Mature protein contains a signal sequence, a pro-domain and a 96 aa mature sequence with several cysteines that are conserved among family members. It circulates as an unglycosylated disulfide-linked homodimer. Like other GDNF family members, Persephin acts through engagement of GRFα4, a glycosylphosphatidylinositol (GPI)-linked GDNF receptor family Persephin is reported to promote both the survival and growth of central dopaminergic and motor neurons, and kidney development. These effects are correlated with the expression patterns of GFRα4, and RET.
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分子量
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Calculated MW: 10.4 kDa
Observed MW: 12 kDa
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基因ID
- 5623
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UniProt
- O60542
抗原
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