Peroxiredoxin 3 Protein (PRDX3) (AA 63-256)
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Quick Overview for Peroxiredoxin 3 Protein (PRDX3) (AA 63-256) (ABIN7318890)
抗原
See all Peroxiredoxin 3 (PRDX3) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 63-256
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原理
- Recombinant Human Peroxiredoxin-3/PRDX3 Protein
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序列
- Pro63-Gln256
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产品特性
- Recombinant Human Peroxiredoxin-3 is produced by our E.coli expression system and the target gene encoding Pro63-Gln256 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, pH 8.0.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- Peroxiredoxin 3 (PRDX3)
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别名
- Peroxiredoxin-3/PRDX3
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背景
- AOP-1,AOP1,Antioxidant Protein 1,HBC189,PRDX3,Peroxiredoxin III,Peroxiredoxin-3,Protein MER5 homolog,Prx-III,Thioredoxin-Dependent Peroxide Reductase Mitochondrial,Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localized in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
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分子量
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Calculated MW: 21.6 kDa
Observed MW: 25 kDa
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基因ID
- 10935
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UniProt
- P30048
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途径
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
抗原
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