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P-Cadherin Protein (CDH3) (Fc Tag)

This Recombinant P-Cadherin protein is expressed in 人细胞.
产品编号 ABIN7320475
发货至: 中国

Quick Overview for P-Cadherin Protein (CDH3) (Fc Tag) (ABIN7320475)

抗原

See all P-Cadherin (CDH3) 蛋白
P-Cadherin (CDH3)

蛋白类型

Recombinant

宿主

  • 14
  • 6
  • 2
  • 1
小鼠

资源

  • 13
  • 6
  • 2
  • 1
  • 1
人细胞

纯度

> 90 % as determined by SDS-PAGE
  • 标记

    This P-Cadherin protein is labelled with Fc Tag.

    原理

    Recombinant Mouse Cadherin-3/CDH3 Protein (Fc Tag)

    序列

    Glu100-Gly647

    产品特性

    Recombinant Mouse Cadherin-3 is produced by our Mammalian expression system and the target gene encoding Glu100-Gly647 is expressed with a Fc tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    P-Cadherin (CDH3)

    别名

    Cadherin-3/CDH3

    背景

    Background: Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.

    Synonym: Cadherin-3, Placental cadherin, P-cadherin, Cdh3

    分子量

    87.5 kDa

    UniProt

    P10287
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