NCF2 蛋白
Quick Overview for NCF2 蛋白 (ABIN7317174)
抗原
See all NCF2 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human NCF2/P67phox Protein
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序列
- Met 1-Val526
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产品特性
- A DNA sequence encoding the human NCF2 (AAH01606.1) (Met1-Val526) was expressed and purified with two additional amino acids (Gly & Pro) at the N-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile 20 mM Tris, 300 mM NaCl, pH 8.0
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))
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别名
- NCF2/P67phox
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背景
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Background: NCF2, also known as NCF-2 and p67phox, is a subunit of the multi-protein NADPH oxidase complex. NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in NCF2 gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms.
Synonym: NCF-2,NOXA2,P67-PHOX,P67PHOX
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分子量
- 59.9 kDa
抗原
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