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Neuroligin 3 Protein (NLGN3) (His tag)

NLGN3 宿主: 人 宿主: HEK-293 Cells Recombinant > 92 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317636
发货至: 中国
  • 抗原 See all Neuroligin 3 (NLGN3) 蛋白
    Neuroligin 3 (NLGN3)
    蛋白类型
    Recombinant
    宿主
    • 8
    • 3
    • 1
    资源
    • 6
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This Neuroligin 3 protein is labelled with His tag.
    原理
    Recombinant Human Neuroligin-3/NLGN3 Protein (His Tag)
    序列
    Met 1-Ser 689
    产品特性
    A DNA sequence encoding the human NLGN3 isoform 2 (Q9NZ94-2) extracellular domain (Met 1-Ser 689) was expressed, fused with a polyhistidine tag at the C-terminus.
    纯度
    > 92 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product NLGN3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Neuroligin 3 (NLGN3)
    别名
    Neuroligin-3/NLGN3 (NLGN3 产品)
    别名
    Nlgn3 Protein, GB18290 Protein, hnl3 Protein, NLGN3 Protein, CCE-L1 Protein, NV16744 Protein, Nv1604741 Protein, HNL3 Protein, A230085M13Rik Protein, NL3 Protein, neuroligin 3 Protein, neuroligin 3 S homeolog Protein, NLG-3 Protein, nlgn3.S Protein, NLGN3 Protein, LOC659852 Protein, LOC100121155 Protein, nlgn3 Protein, Nlgn3 Protein
    背景

    Background: Neuroligin 3 (NLGN3) is a member of the type-B carboxylesterase/lipase family. Neuroligins (NLGNs) are a family of presumptive postsynaptic cell adhesion molecules. Neuroligins (NLs) constitute a family of cell-surface proteins that interact with neurexins (beta-Nxs), another class of neuronal cell-surface proteins, one of each class functioning together in synapse formation. Neuroligins control the formation and functional balance of excitatory and inhibitory synapses in hippocampal neurons. NLGN1 and NLGN2 isoforms are concentrated at glutamatergic and GABAergic synapses, respectively, but the cellular expression and synaptic localization of the endogenous. NLGN3 was enriched in brain, where NLGN3 protein levels increased during postnatal development, coinciding with the peak of synaptogenesis. The NLGN3 is a synaptic adhesion molecule that is a shared component of glutamatergic and GABAergic synapses. Mutations in NLGN3 gene may be associated with autism and Asperger syndrome.

    Synonym: HNL3

    分子量
    74 kDa
    途径
    Synaptic Membrane
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