Neuroligin 3 Protein (NLGN3) (His tag)
Quick Overview for Neuroligin 3 Protein (NLGN3) (His tag) (ABIN7317636)
抗原
See all Neuroligin 3 (NLGN3) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Neuroligin 3 protein is labelled with His tag.
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原理
- Recombinant Human Neuroligin-3/NLGN3 Protein (His Tag)
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序列
- Met 1-Ser 689
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产品特性
- A DNA sequence encoding the human NLGN3 isoform 2 (Q9NZ94-2) extracellular domain (Met 1-Ser 689) was expressed, fused with a polyhistidine tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Neuroligin 3 (NLGN3) (AA 1-828) protein (GST tag)
NLGN3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Neuroligin 3 (NLGN3) protein (Myc-DYKDDDDK Tag)NLGN3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Neuroligin 3 (NLGN3)
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别名
- Neuroligin-3/NLGN3
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背景
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Background: Neuroligin 3 (NLGN3) is a member of the type-B carboxylesterase/lipase family. Neuroligins (NLGNs) are a family of presumptive postsynaptic cell adhesion molecules. Neuroligins (NLs) constitute a family of cell-surface proteins that interact with neurexins (beta-Nxs), another class of neuronal cell-surface proteins, one of each class functioning together in synapse formation. Neuroligins control the formation and functional balance of excitatory and inhibitory synapses in hippocampal neurons. NLGN1 and NLGN2 isoforms are concentrated at glutamatergic and GABAergic synapses, respectively, but the cellular expression and synaptic localization of the endogenous. NLGN3 was enriched in brain, where NLGN3 protein levels increased during postnatal development, coinciding with the peak of synaptogenesis. The NLGN3 is a synaptic adhesion molecule that is a shared component of glutamatergic and GABAergic synapses. Mutations in NLGN3 gene may be associated with autism and Asperger syndrome.
Synonym: HNL3
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分子量
- 74 kDa
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途径
- Synaptic Membrane
抗原
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