Neuroligin 1 Protein (NLGN1) (His tag)
Quick Overview for Neuroligin 1 Protein (NLGN1) (His tag) (ABIN7320172)
抗原
See all Neuroligin 1 (NLGN1) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Neuroligin 1 protein is labelled with His tag.
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原理
- Recombinant Mouse Neuroligin 1/NLGN1 Protein (His Tag)
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序列
- Met 1-Ser 697
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产品特性
- A DNA sequence encoding the mouse NLGN1 isoform 1 (Q99K10-1) extracellular domain (Met 1-Ser 697) was expressed, with a C-terminal polyhistidine tag.
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Neuroligin 1 (NLGN1) (AA 578-677) protein (GST tag)
NLGN1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Neuroligin 1 (NLGN1) (AA 1-823) protein (GST tag)NLGN1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Neuroligin 1 (NLGN1) proteinNLGN1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Neuroligin 1 (NLGN1) protein (Myc-DYKDDDDK Tag)NLGN1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Neuroligin 1 (NLGN1)
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别名
- Neuroligin 1/NLGN1
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背景
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Background: Neuroligin 1 (NLGN1) belongs to the type-B carboxylesterase/lipase family, is a synaptic cell-adhesion molecule that is enriched in postsynaptic densities where it may recruit receptors, channels, and signal-transduction molecules to synaptic sites of cell adhesion. Neuroligins consist of five members (NLGN1, NLGN2, NLGN3, NLGN4 and NLGN4Y), which interact with beta-neurexins and this interaction is involved in the formation of functional synapses. The extracellular domain of functional Neuroligin 1 associates as a dimer when analyzed by sedimentation equilibrium. Neuroligin 1 has a unique N-linked glycosylation pattern in the neuroligin family, and glycosylation and its processing modify neuroligin activity. Neuroligin 1 is a potent trigger for the de novo formation of synaptic connections, and it has recently been suggested that it is required for the maturation of functionally competent excitatory synapses. The persistent expression of Neuroligin 1 is required for the maintenance of NMDAR-mediated synaptic transmission, which enables normal development of synaptic plasticity and long-term memory in the amygdala of adult animals.
Synonym: 6330415N05Rik,BB179718,mKIAA1070,NL1,Nlg1
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分子量
- 73.5 kDa
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途径
- Synaptic Membrane, Synaptic Vesicle Exocytosis
抗原
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