NFASC Protein (His tag)
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Quick Overview for NFASC Protein (His tag) (ABIN7317169)
抗原
See all NFASC 蛋白蛋白类型
宿主
资源
纯度
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标记
- This NFASC protein is labelled with His tag.
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原理
- Recombinant Human NFASC/Neurofascin protein (His Tag)
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序列
- Met 1-Gln939
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产品特性
- A DNA sequence encoding the human NFASC (O94856-12) (Met1-Gln939) was expressed with a C-terminal polyhistidine tag.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Neurofascin (NFASC) protein (Fc Tag)
NFASC 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Neurofascin (NFASC) (AA 1239-1347) protein (His tag)NFASC 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. SDS
Neurofascin (NFASC) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)NFASC 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Neurofascin (NFASC) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)NFASC 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- NFASC (Neurofascin (NFASC))
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别名
- NFASC/Neurofascin
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背景
- NF,NRCAML,NFASC, also known as neurofascin, belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM family. It contains 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. NFASC functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. NFASC links the AIS extracellular matrix to the intracellular cytoskeleton.
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分子量
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Calculated MW: 104.4 kDa
Observed MW: 114-119 kDa
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UniProt
- O948562
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途径
- Cell-Cell Junction Organization
抗原
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