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NFASC Protein (His tag)

This Recombinant NFASC protein is expressed in HEK-293 Cells.
产品编号 ABIN7317169
发货至: 中国

Quick Overview for NFASC Protein (His tag) (ABIN7317169)

抗原

See all NFASC 蛋白
NFASC (Neurofascin (NFASC))

蛋白类型

Recombinant

宿主

资源

  • 3
  • 2
  • 1
HEK-293 Cells

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This NFASC protein is labelled with His tag.

    原理

    Recombinant Human NFASC/Neurofascin protein (His Tag)

    序列

    Met 1-Gln939

    产品特性

    A DNA sequence encoding the human NFASC (O94856-12) (Met1-Gln939) was expressed with a C-terminal polyhistidine tag.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    NFASC (Neurofascin (NFASC))

    别名

    NFASC/Neurofascin

    背景

    Background: NFASC, also known as neurofascin, belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM family. It contains 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. NFASC functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. NFASC links the AIS extracellular matrix to the intracellular cytoskeleton.

    Synonym: NF,NRCAML

    分子量

    104.4 kDa

    途径

    Cell-Cell Junction Organization
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