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NCALD Protein (His tag)

This Recombinant NCALD protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7318816
发货至: 中国
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Quick Overview for NCALD Protein (His tag) (ABIN7318816)

抗原

See all NCALD 蛋白
NCALD (Neurocalcin delta (NCALD))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 90 % as determined by reducing SDS-PAGE.
  • 标记

    This NCALD protein is labelled with His tag.

    原理

    Recombinant Human Neurocalcin-δ/NCALD Protein (His Tag)

    序列

    Met 1-Phe193

    产品特性

    Recombinant Human Neurocalcin-delta is produced by our E.coli expression system and the target gene encoding Met1-Phe193 is expressed with a 6His tag at the N-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, 1 mM DTT, 40 % Glycerol, pH 8.0.

    储存液

    Dithiothreitol (DTT)

    注意事项

    This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    NCALD (Neurocalcin delta (NCALD))

    别名

    Neurocalcin-delta/NCALD

    背景

    NCALD,Neurocalcin-Delta,Neurocalcin-delta (NCALD) is a neuronal calcium-binding protein that belongs to the neuronal calcium sensor (NCS) family. It expressed in mammalian brains. NCALD contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein possesses a Ca2+ /myristoyl switch. It is cytosolic at resting calcium levels. However, elevated intracellular calcium levels induce a conformational change which exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. NCALD protein is thought to be a regulator of G protein-coupled receptor signal transduction.

    分子量

    Calculated MW: 24.4 kDa

    Observed MW: 20 kDa

    基因ID

    83988

    UniProt

    P61601
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