NCALD Protein (His tag)
Quick Overview for NCALD Protein (His tag) (ABIN7318816)
抗原
See all NCALD 蛋白蛋白类型
宿主
资源
纯度
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标记
- This NCALD protein is labelled with His tag.
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原理
- Recombinant Human Neurocalcin-δ/NCALD Protein (His Tag)
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序列
- Met 1-Phe193
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产品特性
- Recombinant Human Neurocalcin-delta is produced by our E.coli expression system and the target gene encoding Met1-Phe193 is expressed with a 6His tag at the N-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 40 % Glycerol, pH 8.0.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- NCALD (Neurocalcin delta (NCALD))
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别名
- Neurocalcin-delta/NCALD
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背景
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Background: Neurocalcin-delta (NCALD) is a neuronal calcium-binding protein that belongs to the neuronal calcium sensor (NCS) family. It expressed in mammalian brains. NCALD contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein possesses a Ca2+ /myristoyl switch. It is cytosolic at resting calcium levels. However, elevated intracellular calcium levels induce a conformational change which exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. NCALD protein is thought to be a regulator of G protein-coupled receptor signal transduction.
Synonym: Neurocalcin-Delta, NCALD
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分子量
- 24.4 kDa
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UniProt
- P61601
抗原
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