电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

NRN1 Protein (His tag)

NRN1 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 85 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317340
发货至: 中国
  • 抗原 See all NRN1 蛋白
    NRN1 (Neuritin 1 (NRN1))
    蛋白类型
    Recombinant
    宿主
    • 8
    • 3
    • 1
    • 1
    • 1
    资源
    • 8
    • 3
    • 2
    • 1
    Baculovirus infected Insect Cells
    标记
    This NRN1 protein is labelled with His tag.
    原理
    Recombinant Human Neuritin/NRN1 Protein (Baculovirus, His Tag)
    序列
    Met 1-Asn 115
    产品特性
    A DNA sequence encoding the mature form of human NRN1 (Q9NPD7) (Met 1-Asn 115) was fused with a polyhistidine tag at the C-terminus.
    纯度
    > 85 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product NRN1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    NRN1 (Neuritin 1 (NRN1))
    别名
    Neuritin/NRN1 (NRN1 产品)
    别名
    NRN Protein, dJ380B8.2 Protein, 0710008J23Rik Protein, Cpg15 Protein, Nrn Protein, neuritin Protein, nrn1 Protein, zgc:92828 Protein, NRN1 Protein, cpg15 Protein, nrn Protein, nrn1-a Protein, nrn1-b Protein, nrn1b Protein, neuritin 1 Protein, neuritin 1a Protein, neuritin 1 S homeolog Protein, neuritin 1 L homeolog Protein, NRN1 Protein, Nrn1 Protein, nrn1a Protein, nrn1 Protein, nrn1.S Protein, nrn1.L Protein
    背景

    Background: Neuritin 1 (NRN1) is a member of neuritin family. Neuritin is a glycosylphosphatidylinositol- anchored protein induced by neural activity. It is expressed in postmitotic-differentiating neurons of the developing nervous system and a population of small-diameter neurons in the dorsal root ganglia and was anterogradely and retrogradely transported. Neuritin message is induced by neuronal activity and by the activity-regulated neurotrophins BDNF, nerve growth factor (NGF) and NT-3. Purified recombinant neuritin promotes neurite outgrowth and arborization in primary embryonic hippocampal and cortical cultures. Thus, neuritin is considered as a downstream effector of activity-induced neurite outgrowth. In clinical, neuritin levels in diabetes were reduced in both dorsal root ganglia and sciatic nerve of rats, and these deficits were reversed in vivo by treatment with NGF. This manipulation of neuritin levels in diabetes may provide a potential target for the therapeutic intervention in the management of neuropathy.

    Synonym: dJ380B8.2,MGC44811,NRN

    UniProt
    Q9NPD7
You are here: