NRN1 Protein (His tag)
Quick Overview for NRN1 Protein (His tag) (ABIN7317340)
抗原
See all NRN1 蛋白蛋白类型
宿主
资源
纯度
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标记
- This NRN1 protein is labelled with His tag.
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原理
- Recombinant Human Neuritin/NRN1 Protein (Baculovirus, His Tag)
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序列
- Met 1-Asn 115
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产品特性
- A DNA sequence encoding the mature form of human NRN1 (Q9NPD7) (Met 1-Asn 115) was fused with a polyhistidine tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Neuritin 1 (NRN1) (AA 28-116) protein (His-IF2DI Tag)
NRN1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Neuritin 1 (NRN1) (AA 1-142) protein (GST tag)NRN1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Neuritin 1 (NRN1) (AA 28-116) protein (His-SUMO Tag)NRN1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- NRN1 (Neuritin 1 (NRN1))
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别名
- Neuritin/NRN1
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背景
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Background: Neuritin 1 (NRN1) is a member of neuritin family. Neuritin is a glycosylphosphatidylinositol- anchored protein induced by neural activity. It is expressed in postmitotic-differentiating neurons of the developing nervous system and a population of small-diameter neurons in the dorsal root ganglia and was anterogradely and retrogradely transported. Neuritin message is induced by neuronal activity and by the activity-regulated neurotrophins BDNF, nerve growth factor (NGF) and NT-3. Purified recombinant neuritin promotes neurite outgrowth and arborization in primary embryonic hippocampal and cortical cultures. Thus, neuritin is considered as a downstream effector of activity-induced neurite outgrowth. In clinical, neuritin levels in diabetes were reduced in both dorsal root ganglia and sciatic nerve of rats, and these deficits were reversed in vivo by treatment with NGF. This manipulation of neuritin levels in diabetes may provide a potential target for the therapeutic intervention in the management of neuropathy.
Synonym: dJ380B8.2,MGC44811,NRN
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UniProt
- Q9NPD7
抗原
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