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- 抗原 See all NOV 蛋白
- NOV (Nephroblastoma Overexpressed (NOV))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- 人细胞
- 标记
- This NOV protein is labelled with His tag.
- 原理
- Recombinant Mouse NOV/CCN3 Protein (His Tag)
- 序列
- Ser26-Ile354
- 产品特性
- Recombinant Mouse Nephroblastoma Overexpressed Gene is produced by our Mammalian expression system and the target gene encoding Ser26-Ile354 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product NOV 蛋白
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Nephroblastoma Overexpressed (NOV) (AA 1-357) protein (GST tag)
NOV 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Nephroblastoma Overexpressed (NOV) (AA 28-357) protein (His tag)NOV 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Nephroblastoma Overexpressed (NOV) (AA 32-131) protein (GST tag)NOV 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Nephroblastoma Overexpressed (NOV) (AA 32-357) protein (His tag)Crystallography grade NOV 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Nephroblastoma Overexpressed (NOV) (AA 22-354) protein (His tag)Crystallography grade NOV 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- NOV (Nephroblastoma Overexpressed (NOV))
- 别名
- NOV/CCN3 (NOV 产品)
- 别名
- CCN3 Protein, IBP-9 Protein, IGFBP-9 Protein, IGFBP9 Protein, NOVh Protein, nov-A Protein, xnov Protein, NovH Protein, C130088N23Rik Protein, nephroblastoma overexpressed Protein, nephroblastoma overexpressed L homeolog Protein, nephroblastoma overexpressed gene Protein, NOV Protein, nov.L Protein, Nov Protein
- 背景
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Background: NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor-binding protein (IGFBP) domain, von Willebrand type C (VWC) domain, thrombospondin-1 (TSP-1) domain, and C-terminal (CT) domain (absent in CCN5). By specific interactions with these domains, CCN proteins modulate multiple signalling pathways including BMPs, Wnt, TGFs, Notch and integrins to regulate cell proliferation, differentiation, adhesion, migration, angiogenesis, and survival. CCN3 is firstly characterized as a promoter of progenitor activity of human hematopoietic stem cells, as knockdown of CCN3 can abrogate the function of primitive progenitors. Recent studies showed that CCN3 is also actively involved in the process of wound healing. CCN3 is highly expressed in granulation tissues of cutaneous wounds and capable of inducing synthetic responses of fibroblasts.
Synonym: Protein NOV homolog, NovH, CCN family member 3, Nephroblastoma-overexpressed gene protein homolog, Nov
- 分子量
- 39.1 kDa
- UniProt
- Q64299
- 途径
- Smooth Muscle Cell Migration, Growth Factor Binding
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