NOV Protein (AA 26-354) (His tag)
This Recombinant NOV protein is expressed in HEK-293 Cells.
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产品编号 ABIN7320620
发货至:
中国
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Quick Overview for NOV Protein (AA 26-354) (His tag) (ABIN7320620)
抗原
See all NOV 蛋白
NOV
(Nephroblastoma Overexpressed (NOV))
蛋白类型
Recombinant
宿主
小鼠
资源
HEK-293 Cells
纯度
> 95 % as determined by reducing SDS-PAGE.
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产品特性
- AA 26-354
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标记
- This NOV protein is labelled with His tag.
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原理
- Recombinant Mouse NOV/CCN3 Protein (His Tag)
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序列
- Ser26-Ile354
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产品特性
- Recombinant Mouse Nephroblastoma Overexpressed Gene is produced by our Mammalian expression system and the target gene encoding Ser26-Ile354 is expressed with a 6His tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Nephroblastoma Overexpressed (NOV) (AA 1-357) protein (GST tag)
NOV 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
Nephroblastoma Overexpressed (NOV) (AA 28-357) protein (His-IF2DI Tag)NOV 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- NOV (Nephroblastoma Overexpressed (NOV))
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别名
- NOV/CCN3
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背景
- CCN family member 3,Nephroblastoma-overexpressed gene protein homolog,Nov,NovH,Protein NOV homolog,NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor-binding protein (IGFBP) domain, von Willebrand type C (VWC) domain, thrombospondin-1 (TSP-1) domain, and C-terminal (CT) domain (absent in CCN5). By specific interactions with these domains, CCN proteins modulate multiple signalling pathways including BMPs, Wnt, TGFs, Notch and integrins to regulate cell proliferation, differentiation, adhesion, migration, angiogenesis, and survival. CCN3 is firstly characterized as a promoter of progenitor activity of human hematopoietic stem cells, as knockdown of CCN3 can abrogate the function of primitive progenitors. Recent studies showed that CCN3 is also actively involved in the process of wound healing. CCN3 is highly expressed in granulation tissues of cutaneous wounds and capable of inducing synthetic responses of fibroblasts.
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分子量
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Calculated MW: 37.1 kDa
Observed MW: 50 kDa
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UniProt
- Q64299
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途径
- Smooth Muscle Cell Migration, Growth Factor Binding
抗原
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