MYOC Protein (His tag)
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北京 101111
Quick Overview for MYOC Protein (His tag) (ABIN7197075)
抗原
See all MYOC 蛋白蛋白类型
宿主
资源
纯度
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标记
- This MYOC protein is labelled with His tag.
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原理
- Recombinant Human MYOC/Myocilin Protein (His Tag)
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序列
- Met 1-Met 504
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产品特性
- A DNA sequence encoding the full length of human MYOC (Q99972) (Met 1-Met 504) was fused with a polyhistidine tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Myocilin (MYOC) (AA 36-135) protein (GST tag)
MYOC 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Myocilin (MYOC) (AA 1-504) protein (GST tag)MYOC 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Myocilin (MYOC) protein (Myc-DYKDDDDK Tag)MYOC 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- MYOC (Myocilin (MYOC))
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别名
- MYOC/Myocilin
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背景
- GLC1A,GPOA,JOAG,JOAG1,TIGR,myocilin,Myocilin, also known as Trabecular meshwork-induced glucocorticoid response protein, MYOC and GLC1A, is a protein which contains oneolfactomedin-like domain. Myocilin / MYOC may participate in the obstruction of fluid outflow in the trabecular meshwork. Myocilin / MYOC is expressed in large amounts in various types of muscle, ciliary body, papillary sphincter, skeletal muscle, heart and other tissues. Myocilin / MYOC is expressed predominantly in the retina. In normal eyes, it is found in the inner uveal meshwork region and the anterior portion of the meshwork. In contrast, in many glaucomatous eyes, it is found in more regions of the meshwork and appeared more intensively than in normal eyes, regardless of the type or clinical severity of glaucoma. Defects in Myocilin / MYOC may contribute to primary congenital glaucoma type 3A (GLC3A). Defects in MYOC may also contribute to this phenotype via digenic inheritance. GLC3A is an autosomal recessive form of primary congenital glaucoma (PCG). PCG is characterized by marked increase of intraocular pressure at birth or early choldhood, large ocular globes (buphthalmos) and corneal edema.
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分子量
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Calculated MW: 54.7 kDa
Observed MW: 33 kDa
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基因ID
- 4653
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UniProt
- Q99972
抗原
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