Myelin Protein (AA 30-153) (His tag)
This Recombinant Myelin protein is expressed in HEK-293 Cells.
产品编号 ABIN7318793
发货至:
中国
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Quick Overview for Myelin Protein (AA 30-153) (His tag) (ABIN7318793)
抗原
Myelin
蛋白类型
Recombinant
宿主
人
资源
HEK-293 Cells
纯度
> 95 % as determined by reducing SDS-PAGE.
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产品特性
- AA 30-153
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标记
- This Myelin protein is labelled with His tag.
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原理
- Recombinant Human Myelin Protein P0/MPZ Protein (His Tag)
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序列
- Ile30-Arg153
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产品特性
- Recombinant Human Myelin Protein P0 is produced by our Mammalian expression system and the target gene encoding Ile30-Arg153 is expressed with a 6His tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Myelin
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背景
- MPP,MPZ,Myelin Peripheral Protein,Myelin Protein P0,Myelin Protein Zero,Myelin Protein P0 (MPZ) is a single-pass type I membrane glycoprotein which belongs to the myelin P0 protein family. MPZ contains one Ig-like V-type (immunoglobulin-like) domain, absent in the central nervous system. MPZ is a major component of the myelin sheath in peripheral nerves. It is postulated that MPZ is a structural element in the formation and stabilisation of peripheral nerve myelin, holding its characteristic coil structure together by the interaction of its positively-charged domain with acidic lipids in the cytoplasmic face of the opposed bilayer, and by interaction between hydrophobic globular of adjacent extracellular domains. Defects in MPZ associated with Charcot-Marie-Tooth disease and Dejerine-Sottas disease.
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分子量
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Calculated MW: 15.2 kDa
Observed MW: 14-17 kDa
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基因ID
- 4359
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UniProt
- P25189
抗原
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