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MVK Protein (His-GST)

This Recombinant MVK protein is expressed in Baculovirus infected Insect Cells.
产品编号 ABIN7197016
发货至: 中国
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Quick Overview for MVK Protein (His-GST) (ABIN7197016)

抗原

See all MVK 蛋白
MVK (Mevalonate Kinase (MVK))

蛋白类型

Recombinant

宿主

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资源

  • 7
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Baculovirus infected Insect Cells

纯度

> 90 % as determined by reducing SDS-PAGE.
  • 标记

    This MVK protein is labelled with His-GST.

    原理

    Recombinant Human MVK/Mevalonate kinase Protein (His & GST Tag)

    序列

    Met 1-Leu 396

    产品特性

    A DNA sequence encoding the human MVK (Q03426) (Met1-Leu396) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 116,946.14 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 145,985.55 ¥

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  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, 2 mM DTT, pH 7.4, 10 % glycerol

    储存液

    Dithiothreitol (DTT)

    注意事项

    This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    MVK (Mevalonate Kinase (MVK))

    别名

    MVK/Mevalonate kinase

    背景

    LRBP,MK,MVLK,POROK3,Mevalonate kinase belongs to the GHMP kinase family, Mevalonate kinase subfamily. It can be found in a wide variety of organisms from bacteria to mammals. Mevalonate kinase may be a regulatory site in cholesterol biosynthetic pathway. Defects in mevalonate kinase can cause mevalonic aciduria (MEVA). It is an accumulation of mevalonic acid which causes a variety of symptoms such as psychomotor retardation, dysmorphic features, cataracts, hepatosplenomegaly, lymphadenopathy, anemia, hypotonia, myopathy, and ataxia. Defects in mevalonate kinase can also cause hyperimmunoglobulinemia D and periodic fever syndrome (HIDS). HIDS is an autosomal recessive disease characterized by recurrent episodes of unexplained high fever associated with skin rash, diarrhea, adenopathy (swollen, tender lymph nodes), athralgias and/or arthritis.

    分子量

    Calculated MW: 70.2 kDa

    Observed MW: 47 kDa

    基因ID

    4598

    UniProt

    Q03426
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