MVK Protein (His-GST)
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Quick Overview for MVK Protein (His-GST) (ABIN7197016)
抗原
See all MVK 蛋白蛋白类型
宿主
资源
纯度
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标记
- This MVK protein is labelled with His-GST.
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原理
- Recombinant Human MVK/Mevalonate kinase Protein (His & GST Tag)
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序列
- Met 1-Leu 396
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产品特性
- A DNA sequence encoding the human MVK (Q03426) (Met1-Leu396) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 116,946.14 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 145,985.55 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, 2 mM DTT, pH 7.4, 10 % glycerol
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储存液
- Dithiothreitol (DTT)
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注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- MVK (Mevalonate Kinase (MVK))
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别名
- MVK/Mevalonate kinase
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背景
- LRBP,MK,MVLK,POROK3,Mevalonate kinase belongs to the GHMP kinase family, Mevalonate kinase subfamily. It can be found in a wide variety of organisms from bacteria to mammals. Mevalonate kinase may be a regulatory site in cholesterol biosynthetic pathway. Defects in mevalonate kinase can cause mevalonic aciduria (MEVA). It is an accumulation of mevalonic acid which causes a variety of symptoms such as psychomotor retardation, dysmorphic features, cataracts, hepatosplenomegaly, lymphadenopathy, anemia, hypotonia, myopathy, and ataxia. Defects in mevalonate kinase can also cause hyperimmunoglobulinemia D and periodic fever syndrome (HIDS). HIDS is an autosomal recessive disease characterized by recurrent episodes of unexplained high fever associated with skin rash, diarrhea, adenopathy (swollen, tender lymph nodes), athralgias and/or arthritis.
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分子量
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Calculated MW: 70.2 kDa
Observed MW: 47 kDa
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基因ID
- 4598
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UniProt
- Q03426
抗原
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