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METAP1 蛋白

This Recombinant METAP1 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7319523
发货至: 中国

Quick Overview for METAP1 蛋白 (ABIN7319523)

抗原

See all METAP1 蛋白
METAP1 (Methionyl Aminopeptidase 1 (METAP1))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human METAP1 Protein

    序列

    Met1-Phe386

    产品特性

    Recombinant Human METAP1 is produced by our E.coli expression system and the target gene encoding Met1-Phe386 is expressed.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Frozen, Liquid

    缓冲液

    Supplied as a 0.2 μm filtered solution of 20 mM Tris,500 mM NaCl,10 % glycerol, pH 8.0.

    储存条件

    -20 °C

    储存方法

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原

    METAP1 (Methionyl Aminopeptidase 1 (METAP1))

    别名

    METAP1

    背景

    Background: Methionine Aminopeptidase 1 is a member of the M24 family of metalloproteases. METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents. METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine aminopeptidases (MetAPs) and is essential for cell growth. Inhibition of METAPs provides a novel strategy in developing anti-cancer drugs.

    Synonym: Methionine aminopeptidase 1, MAP 1, MetAP 1, Peptidase M 1, METAP1,MAP1A,MetAP1A

    分子量

    43.2 kDa

    UniProt

    P53582

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling
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