MIF 蛋白
Quick Overview for MIF 蛋白 (ABIN7318757)
抗原
See all MIF 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human MIF Protein
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序列
- Met 1-Ala115
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产品特性
- Recombinant Human Macrophage migration inhibitory factor is produced by our E.coli expression system and the target gene encoding Met1-Ala115 is expressed.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (Active) protein
MIF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (AA 2-115) protein (His tag)MIF 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (AA 2-115) protein (Fc Tag)MIF 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (Active) proteinMIF 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (AA 1-115) protein (His tag)MIF 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (AA 1-115) protein (His tag)MIF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (AA 2-115) protein (His-IF2DI Tag)MIF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (AA 1-115) protein (GST tag)MIF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (AA 1-115) protein (GST tag)MIF 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) protein (His tag)MIF 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,20 % Glycerol, pH 7.4.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- MIF (Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF))
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别名
- MIF
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背景
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Background: Human MIF is a 12.5 kDa, 115 amino acid (aa) nonglycosylated polypeptide that is synthesized without asignal sequence .Secretion occurs nonclassically via an ABCA1 transporter.Pro-inflammatory cytokine.Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites ofinflammation suggests a role as mediator in regulating the function of acrophages in host defense.Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase anddopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clearwhether the tautomerase activity has any physiological relevance, and whether it is important for cytokineactivity.
Synonym: Macrophage migration inhibitory factor, MIF, MMIF, Glycosylation-inhibiting factor, GLIF, L-dopachrome tautomerase, Phenylpyruvate tautomerase
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分子量
- 12.5 kDa
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UniProt
- P14174
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
抗原
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