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Quick Overview for LY9 Protein (His tag) (ABIN7320715)
抗原
See all LY9 (CD229) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This LY9 protein is labelled with His tag.
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原理
- Recombinant Mouse SLAMF3/CD229 Protein (His Tag)
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序列
- Lys48-Phe454
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产品特性
- Recombinant Mouse T-lymphocyte surface antigen Ly-9 is produced by our Mammalian expression system and the target gene encoding Lys48-Phe454 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Lymphocyte Antigen 9 (CD229) (AA 48-454) (Active) protein (His-Avi Tag)
CD229 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Lymphocyte Antigen 9 (CD229) (AA 48-454) (Active) protein (Biotin,His-Avi Tag)CD229 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Lymphocyte Antigen 9 (CD229) (AA 1-193) protein (GST tag)CD229 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Lymphocyte Antigen 9 (CD229) (AA 48-454) protein (Fc Tag)CD229 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Lymphocyte Antigen 9 (CD229) (AA 48-454) protein (His tag)CD229 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Lymphocyte Antigen 9 (CD229) (AA 48-454) protein (His tag)CD229 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % SDS
Lymphocyte Antigen 9 (CD229) (AA 48-454) (Active) protein (His tag,AVI tag,Biotin)CD229 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
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别名
- SLAMF3/CD229
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背景
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Background: CD229(SLAMF3) is a type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family. Mature mouse CD229 consists of a 406 aa extracellular domain (ECD) with two Ig-like V-set and two Ig-like truncated C2-set domains, a 21 aa transmembrane segment, and a 180 aa cytoplasmic domain with two immunoreceptor tyrosinebased switch motifs ITSMs. Within the first two Ig-like domains that are common to all SLAM proteins, mouse CD229 shares 22 % -36 % aa sequence identity with mouse 2B4, BLAME, CD2F10,CD84, CRACC, NTBA, and SLAM. CD229 is expressed on T, B, and NK cells, thymocytes and monocytes. Homophilic binding between CD229 Molecules is mediated by the N-terminal Ig-like domain. Human and mouse CD229 exhibit crossspecies binding. Antigen stimulation of lymphocytes induces CD229 clustering to sites of T cell-B cell contact. Antibody ligation of CD229 can inhibit T cell activation, but CD229 knockout mice show impaired T cell immune responses, suggesting a potential role for CD229 in T cell activation or costimulation.
Synonym: T-lymphocyte surface antigen Ly-9, Cell surface molecule Ly-9, Lymphocyte antigen 9, SLAM family member 3, SLAMF3, Signaling lymphocytic activation molecule 3, CD229, Ly9, Ly-9,AI893573, Lgp100, T100
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分子量
- 47 kDa
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NCBI登录号
- NP_032560
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途径
- BCR Signaling
抗原
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