Lipocalin 2 Protein (LCN2) (His tag)
Quick Overview for Lipocalin 2 Protein (LCN2) (His tag) (ABIN7320752)
抗原
See all Lipocalin 2 (LCN2) 蛋白蛋白类型
宿主
资源
纯度
-
-
标记
- This Lipocalin 2 protein is labelled with His tag.
-
原理
- Recombinant Mouse NGAL/Lipocalin-2 Protein (His Tag)
-
序列
- Gln21-Asn200
-
产品特性
- Recombinant Mouse Neutrophil gelatinase-associated lipocalin is produced by our Mammalian expression system and the target gene encoding Gln21-Asn200 is expressed with a 6His tag at the C-terminus.
-
内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
-
-
Lipocalin 2 (LCN2) (AA 21-198) protein (Fc Tag)
LCN2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Lipocalin 2 (LCN2) (AA 21-198) protein (His tag)LCN2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Lipocalin 2 (LCN2) (AA 21-198) protein (His tag)LCN2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Lipocalin 2 (LCN2) (AA 21-200) protein (Fc Tag)LCN2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Lipocalin 2 (LCN2) (AA 1-198) protein (GST tag)LCN2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Lipocalin 2 (LCN2) (Active) protein (His tag)LCN2 宿主: 大鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE Active
Lipocalin 2 (LCN2) (Active) protein (His tag)LCN2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
-
-
限制
- 仅限研究用
-
-
-
状态
- Frozen, Liquid
-
缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, 10 % Glycerol, pH 5.5.
-
储存条件
- -20 °C
-
储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
-
- Lipocalin 2 (LCN2)
-
别名
- NGAL/Lipocalin-2
-
背景
-
Background: Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes with matrix metalloproteinase-9 (MMP-9) through disulfide bonds. Similar to other lipocalin family members, Lipocalin-2 is involved in diverse cellular processes, including the transport of small hydrophobic molecules, protection of MMP-9 from proteolytic degradation, and cell signaling. Furthermore, Lipocalin-2 can tightly bind to bacterial siderophore through a cell surface receptor, possibly serving as a potent bacteriostatic agent by sequestering iron, regulating innate immunity and protecting kidney epithelial cells from ischemia-reperfusion injury. This protein is mainly expressed in neutrophils and in lower levels in the kidney, prostate, and epithelia of the respiratory and alimentary tracts. Recent evidence also suggests its role as a biomarker for renal injury and inflammation.
Synonym: Neutrophil gelatinase-associated lipocalin, NGAL, Lipocalin-2, SV-40-induced 24P3 protein, Siderocalin LCN2, p25, LCN2
-
分子量
- 21.9 kDa
-
UniProt
- P11672
-
途径
- Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis
抗原
-
