KIF1BP Protein (His-GST)
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Quick Overview for KIF1BP Protein (His-GST) (ABIN7317164)
抗原
See all KIF1BP (KIAA1279) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This KIF1BP protein is labelled with His-GST.
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原理
- Recombinant Human KIAA1279 Protein (His & GST Tag)
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序列
- Met 1-Thr621
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产品特性
- A DNA sequence encoding the human KIAA1279 (Q96EK5) (Met1-Thr621) was expressed with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- KIF1BP (KIAA1279) (KIAA1279)
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别名
- KIAA1279
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背景
- KBP,KIAA1279,TTC20,KIFBP (Kinesin Family Binding Protein, also known as KIAA1279 and KIF1BP) is a Protein Coding gene. This gene encodes a kinesin family member 1 binding protein that is characterized by two tetratricopeptide repeats. The encoded protein localizes to the mitochondria and may be involved in regulating the transport of the mitochondria. Homozygous nonsense mutations in KIAA1279 at 1q22.1, encoding a protein with two tetratricopeptide repeats, underlie this syndromic form of Hirschsprung disease and generalized polymicrogyria, establishing the importance of KIAA1279 in both enteric and central nervous system development. KIAA1279 is widely expressed in the brain, testis, and other tissues. Diseases associated with KIFBP include Goldberg-Shprintzen Syndrome and Shprintzen-Goldberg Craniosynostosis Syndrome.
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分子量
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Calculated MW: 99.6 kDa
Observed MW: 92-102 kDa
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基因ID
- 26128
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UniProt
- Q96EK5
抗原
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