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IL-4 Protein (His tag)

This Recombinant IL-4 protein is expressed in 人细胞.
产品编号 ABIN7320597
发货至: 中国

Quick Overview for IL-4 Protein (His tag) (ABIN7320597)

抗原

See all IL-4 (IL4) 蛋白
IL-4 (IL4) (Interleukin 4 (IL4))

蛋白类型

Recombinant

宿主

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小鼠

资源

  • 54
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人细胞

纯度

> 95 % as determined by SDS-PAGE
  • 标记

    This IL-4 protein is labelled with His tag.

    原理

    Recombinant Mouse Interleukin-4/IL-4 Protein (His Tag)

    序列

    His21-Ser140

    产品特性

    Recombinant Mouse Interleukin-4 is produced by our Mammalian expression system and the target gene encoding His21-Ser140 is expressed with a 6His tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    IL-4 (IL4) (Interleukin 4 (IL4))

    别名

    Interleukin-4/IL-4

    背景

    Background: Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.

    Synonym: Interleukin-4, IL-4, IL4, B-cell IgG differentiation factor, B-cell growth factor 1, B-cell stimulatory factor 1, BSF-1, IGG1 induction factor, Lymphocyte stimulatory factor 1

    分子量

    14.6 kDa

    UniProt

    P07750

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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