IL-22 Protein (AA 34-179)
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北京 101111
Quick Overview for IL-22 Protein (AA 34-179) (ABIN7319555)
抗原
See all IL-22 (IL22) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 34-179
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原理
- Recombinant Human Interleukin-22/IL-22 Protein
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序列
- Ala34-Ile179
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产品特性
- Recombinant Human Interleukin-22 is produced by our Mammalian expression system and the target gene encoding Ala34-Ile179 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Interleukin 22 (IL22) (AA 34-179) (Active) protein (His tag)
IL22 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Interleukin 22 (IL22) (AA 34-179) (Active) protein (His tag)IL22 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 22 (IL22) (AA 34-179) (Active) protein (Biotin,His-Avi Tag)IL22 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Interleukin 22 (IL22) (AA 34-179) (Active) protein (His tag,AVI tag,Biotin)IL22 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 22 (IL22) (AA 1-179) protein (GST tag)IL22 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Interleukin 22 (IL22) (AA 34-179) (Active) protein (His tag)IL22 宿主: 人 宿主: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. WB, SDS, ELISA, Imm, AcA Active
Interleukin 22 (IL22) (AA 27-172) protein (His tag)IL22 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Interleukin 22 (IL22) (AA 34-179) protein (mFc Tag)IL22 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Interleukin 22 (IL22) (AA 34-179) (Active) protein (His tag)IL22 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 98 % as determined by reducing SDS-PAGE. CC Active
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- IL-22 (IL22) (Interleukin 22 (IL22))
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别名
- Interleukin-22/IL-22
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背景
- UNQ,IL-D,Interleukin,Cytokine Zcyto,TIFIL,zcyto,IL22,IL-22,IL-D110,IL-TIF,ILTIF,TIFIL-23,TIFa,zcyto18,UNQ3099/PRO10096,UNQ3099,Interleukin-22,Cytokine Zcyto18,IL-10-related T-cell-derived-inducible factor,PRO10096,IL-D110,ILTIF,IL-TIF,TIFa,TIFIL-23,zcyto18,Interleukin-22(IL-22) is a member of a group of the IL-10 family, a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells. IL-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction. It can initiate and regulate innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 likely plays a role in the coordinated response of both adaptive and innate immune systems. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. Biological activity of IL-22 is initiated by binding to a cell-surface complex consisting of IL-22R1 and IL-10R2 receptor chains. IL-22 biological activity is further regulated by interactions with a soluble binding protein, IL-22BP. IL-22BP and an extracellular region of IL-22R1 share sequence similarity. In some cases, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by cytokine IL-17A.
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分子量
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Calculated MW: 17.9 kDa
Observed MW: 25-35 kDa
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基因ID
- 50616
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UniProt
- Q9GZX6
抗原
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