IL-22 Protein (AA 34-179) (mFc Tag)
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Quick Overview for IL-22 Protein (AA 34-179) (mFc Tag) (ABIN7320587)
抗原
See all IL-22 (IL22) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 34-179
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标记
- This IL-22 protein is labelled with mFc Tag.
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原理
- Recombinant Mouse Interleukin-22/IL-22 Protein (mFc Tag)
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序列
- Leu34-Val179
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产品特性
- Recombinant Mouse Interleukin-22 is produced by our Mammalian expression system and the target gene encoding Leu34-Val179 is expressed with a mFc tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- IL-22 (IL22) (Interleukin 22 (IL22))
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别名
- Interleukin-22/IL-22
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背景
- Interleukin,Cytokine Zcyto,IL-D,TIFIL,Cytokine Zcyto18,IL-10-related T-cell-derived-inducible factor,IL-22a,IL-D110,IL-TIF,Interleukin-22a,TIFa,TIFIL-23,UNQ3099/PRO10096,zcyto18,Interleukin-22,T-cell-derived-inducible,factor(IL-TIF),Interleukin-22a(IL-22a),IL-TIF alpha,IL-10-related,IL-22,Il22a,Iltif,Iltifa,Il22,TIFa,Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cleaved to generate a 147 amino acid mature protein that shares approximately 79 % and 22 % sequence identity with human IL22 and IL10, respectively. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10Rβ (previously known as CRF2-4), belonging to the class II cytokine receptor family.
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分子量
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Calculated MW: 43.8 kDa
Observed MW: 50-65 kDa
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基因ID
- 50929
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UniProt
- Q9JJY9
抗原
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