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IL-22 Protein (mFc Tag)

This Recombinant IL-22 protein is expressed in 人细胞.
产品编号 ABIN7320587
发货至: 中国

Quick Overview for IL-22 Protein (mFc Tag) (ABIN7320587)

抗原

See all IL-22 (IL22) 蛋白
IL-22 (IL22) (Interleukin 22 (IL22))

蛋白类型

Recombinant

宿主

  • 25
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小鼠

资源

  • 18
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人细胞

纯度

> 95 % as determined by SDS-PAGE
  • 标记

    This IL-22 protein is labelled with mFc Tag.

    原理

    Recombinant Mouse Interleukin-22/IL-22 Protein (mFc Tag)

    序列

    Leu34-Val179

    产品特性

    Recombinant Mouse Interleukin-22 is produced by our Mammalian expression system and the target gene encoding Leu34-Val179 is expressed with a mFc tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    IL-22 (IL22) (Interleukin 22 (IL22))

    别名

    Interleukin-22/IL-22

    背景

    Background: Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cleaved to generate a 147 amino acid mature protein that shares approximately 79 % and 22 % sequence identity with human IL22 and IL10, respectively. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10Rβ (previously known as CRF2-4), belonging to the class II cytokine receptor family.

    Synonym: Interleukin-22, IL-22, IL-TIF alpha, IL-10-related T-cell-derived-inducible factor, IL-TIF, IL22, Interleukin-22a, IL-22a

    分子量

    43.8 kDa

    UniProt

    Q9JJY9
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