IL17F Protein (AA 31-163)
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Quick Overview for IL17F Protein (AA 31-163) (ABIN7318652)
抗原
See all IL17F 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 31-163
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原理
- Recombinant Human Interleukin-17F/IL-17F Protein
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序列
- Arg31-Gln163
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产品特性
- Recombinant Human Interleukin-17F is produced by our Mammalian expression system and the target gene encoding Arg31-Gln163 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- IL17F (Interleukin 17F (IL17F))
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别名
- Interleukin-17F/IL-17F
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背景
- Cytokine ML,Interleukin,CANDF,IL17F,CANDF6,IL-17F,ML-1,ML1,Cytokine ML-1,IL24,IL-24,Interleukin-17F,Interleukin-24,Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated, but not resting, CD4+ T-cells and activated monocytes. IL-17F has been shown to stimulate the production of several other cytokines, including IL-6, IL-8, and granulocyte colony-stimulating factor. IL-17F can regulate cartilage matrix turnover and stimulates PBMC and T-cell proliferation. IL-17F is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. Defects in IL-17F are the cause of familial candidiasis type 6 (CANDF6).
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分子量
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Calculated MW: 14.9 kDa
Observed MW: 18 kDa
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基因ID
- 112744
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UniProt
- Q96PD4
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途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
抗原
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