IL17F Protein (AA 31-163) (His tag)
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北京 101111
Quick Overview for IL17F Protein (AA 31-163) (His tag) (ABIN7318651)
抗原
See all IL17F 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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产品特性
- AA 31-163
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标记
- This IL17F protein is labelled with His tag.
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原理
- Recombinant Human Interleukin-17F/IL-17F Protein
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序列
- Arg31-Gln163
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产品特性
- Recombinant Human Interleukin-17F is produced by our E.coli expression system and the target gene encoding Arg31-Gln163 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 0.1 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Measure by its ability to induce IL-6 secretion in 3T3 cells. The ED50 for this effect is <20 ng/mL.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile 20 mM sodium acetate, pH 4.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- IL17F (Interleukin 17F (IL17F))
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别名
- Interleukin-17F/IL-17F
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背景
- Cytokine ML,Interleukin,CANDF,IL17F,CANDF6,IL-17F,ML-1,ML1,Cytokine ML-1,IL24,IL-24,Interleukin-17F,Interleukin-24,Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.
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分子量
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Calculated MW: 15.8 kDa
Observed MW: 18 kDa
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基因ID
- 112744
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UniProt
- Q96PD4
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途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
抗原
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