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IL17F Protein (AA 31-163) (His tag)

This Recombinant IL17F protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7318651
发货至: 中国
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Quick Overview for IL17F Protein (AA 31-163) (His tag) (ABIN7318651)

抗原

See all IL17F 蛋白
IL17F (Interleukin 17F (IL17F))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 21
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资源

  • 16
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大肠杆菌(E. Coli)

应用范围

Cell Culture (CC)

纯度

> 98 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 31-163

    标记

    This IL17F protein is labelled with His tag.

    原理

    Recombinant Human Interleukin-17F/IL-17F Protein

    序列

    Arg31-Gln163

    产品特性

    Recombinant Human Interleukin-17F is produced by our E.coli expression system and the target gene encoding Arg31-Gln163 is expressed.

    过滤

    0.2 μm filtered

    内毒素水平

    < 0.1 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Measure by its ability to induce IL-6 secretion in 3T3 cells. The ED50 for this effect is <20 ng/mL.
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile 20 mM sodium acetate, pH 4.0.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    IL17F (Interleukin 17F (IL17F))

    别名

    Interleukin-17F/IL-17F

    背景

    Cytokine ML,Interleukin,CANDF,IL17F,CANDF6,IL-17F,ML-1,ML1,Cytokine ML-1,IL24,IL-24,Interleukin-17F,Interleukin-24,Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.

    分子量

    Calculated MW: 15.8 kDa

    Observed MW: 18 kDa

    基因ID

    112744

    UniProt

    Q96PD4

    途径

    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
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