IL-13 Protein (mFc Tag)
Quick Overview for IL-13 Protein (mFc Tag) (ABIN7319863)
抗原
See all IL-13 (IL13) 蛋白蛋白类型
宿主
资源
纯度
-
-
标记
- This IL-13 protein is labelled with mFc Tag.
-
原理
- Recombinant Human Interleukin-13/IL-13 (C-mFc)
-
序列
- Gly21--Asn132
-
产品特性
- Recombinant Human Interleukin-13 is produced by our Mammalian expression system and the target gene encoding Gly21-Asn132 is expressed with a mFc tag at the C-terminus.
-
内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
-
-
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Please refer to the printed manual for detailed information.
-
缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
-
- IL-13 (IL13) (Interleukin 13 (IL13))
-
别名
- Interleukin-13/IL-13
-
背景
-
Background: Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.
Synonym: Interleukin-13, IL-13
-
分子量
- 38.7 kDa
-
途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
抗原
-