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IL-13 Protein (mFc Tag)

This Recombinant IL-13 protein is expressed in 人细胞.
产品编号 ABIN7319863
发货至: 中国

Quick Overview for IL-13 Protein (mFc Tag) (ABIN7319863)

抗原

See all IL-13 (IL13) 蛋白
IL-13 (IL13) (Interleukin 13 (IL13))

蛋白类型

Recombinant

宿主

  • 21
  • 15
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资源

  • 29
  • 13
  • 8
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  • 2
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  • 1
人细胞

纯度

>95 % as determined by reducing SDS-PAGE.
  • 标记

    This IL-13 protein is labelled with mFc Tag.

    原理

    Recombinant Human Interleukin-13/IL-13 (C-mFc)

    序列

    Gly21--Asn132

    产品特性

    Recombinant Human Interleukin-13 is produced by our Mammalian expression system and the target gene encoding Gly21-Asn132 is expressed with a mFc tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    IL-13 (IL13) (Interleukin 13 (IL13))

    别名

    Interleukin-13/IL-13

    背景

    Background: Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.

    Synonym: Interleukin-13, IL-13

    分子量

    38.7 kDa

    途径

    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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