ITGA5 Protein (His tag)
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- 抗原 See all ITGA5 蛋白
- ITGA5 (Integrin, alpha 5 (ITGA5))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 人细胞
- 标记
- This ITGA5 protein is labelled with His tag.
- 原理
- Recombinant Human ITGA5 Protein (His Tag)(Active)
- 序列
- Phe42-Tyr995
- 产品特性
- Recombinant Human Integrin α-5 is produced by our Mammalian expression system and the target gene encoding Phe42-Tyr995 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human NovoNectin(Cat: PKSH032450) at 2μg/ml(100 μl/well) can bind Human ITGA5-His. The ED50 of Human ITGA5-His is 18.9 ug/ml .
- Top Product
- Discover our top product ITGA5 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- ITGA5 (Integrin, alpha 5 (ITGA5))
- 别名
- ITGA5 (ITGA5 产品)
- 别名
- ITGA5 Protein, Cd49e Protein, Fnra Protein, VLA5 Protein, CD49e Protein, FNRA Protein, VLA5A Protein, Itga5_retired Protein, integrin subunit alpha 5 Protein, integrin alpha 5 (fibronectin receptor alpha) Protein, ITGA5 Protein, Itga5 Protein
- 背景
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Background: Integrin α-5 belongs to the Integrin α chain family and contains 7 FG-GAP repeats. Integrin α-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. It is expressed on fibroblasts, endothelial cells, peripheral T cells and platelets. Integrin α-5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains. In addition to adhesion, ITGA5 participates in cell-surface mediated signalling.
Synonym: Integrin Alpha-5, CD49 Antigen-Like Family Member E, Fibronectin Receptor Subunit Alpha, Integrin Alpha-F, VLA-5, CD49e, ITGA5, FNRA
- 分子量
- 105.1 kDa
- UniProt
- P08648
- 途径
- Integrin Complex
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