ITGA5 Protein (His tag)
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北京 101111
Quick Overview for ITGA5 Protein (His tag) (ABIN7318632)
抗原
See all ITGA5 蛋白蛋白类型
生物活性
宿主
资源
纯度
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标记
- This ITGA5 protein is labelled with His tag.
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原理
- Recombinant Human ITGA5 Protein (His Tag)(Active)
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序列
- Phe42-Tyr995
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产品特性
- Recombinant Human Integrin α-5 is produced by our Mammalian expression system and the target gene encoding Phe42-Tyr995 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Biological Activity Comment
- Immobilized Human NovoNectin(Cat: PKSH032450) at 2μg/ml(100 μl/well) can bind Human ITGA5-His. The ED50 of Human ITGA5-His is 18.9 ug/ml .
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Integrin, alpha 5 (ITGA5) protein (GST tag)
ITGA5 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Integrin, alpha 5 (ITGA5) proteinITGA5 宿主: Cow 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
Integrin, alpha 5 (ITGA5) protein (Myc-DYKDDDDK Tag)ITGA5 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- ITGA5 (Integrin, alpha 5 (ITGA5))
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别名
- ITGA5
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背景
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Background: Integrin α-5 belongs to the Integrin α chain family and contains 7 FG-GAP repeats. Integrin α-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. It is expressed on fibroblasts, endothelial cells, peripheral T cells and platelets. Integrin α-5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains. In addition to adhesion, ITGA5 participates in cell-surface mediated signalling.
Synonym: Integrin Alpha-5, CD49 Antigen-Like Family Member E, Fibronectin Receptor Subunit Alpha, Integrin Alpha-F, VLA-5, CD49e, ITGA5, FNRA
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分子量
- 105.1 kDa
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UniProt
- P08648
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途径
- Integrin Complex
抗原
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