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IGF2 蛋白

This Recombinant IGF2 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7318628
发货至: 中国

Quick Overview for IGF2 蛋白 (ABIN7318628)

抗原

See all IGF2 蛋白
IGF2 (Insulin-Like Growth Factor 2 (IGF2))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human IGF-II/IGF2 Protein (Active)

    序列

    Ala25-Glu91

    产品特性

    Recombinant Human Long Insulin-Like Growth Factor II is produced by our E.coli expression system and the target gene encoding Ala25-Glu91 is expressed.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.

    Biological Activity Comment

    Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. The ED50 for this effect is 15.7 ng/ml.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 5 mM Hac, pH ~3.0.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    IGF2 (Insulin-Like Growth Factor 2 (IGF2))

    别名

    IGF-II/IGF2

    背景

    Background: Insulin-Like Growth Factor II (IGF2) belongs to the insulin family of polypeptide growth factors that is involved in development and growth. Members of this family are structurally homologous to proinsulin, and share higher sequence identity. IGF2 is expressed only from the paternally inherited allele and believed to be secreted by the liver and to circulate in the blood. IGF2 possess growth-promoting activity and can stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGF2 is influenced by placental lactogen and may play a role in fetal development.

    Synonym: Insulin-Like Growth Factor II, IGF-II, Somatomedin-A, IGF2, PP1446

    分子量

    8.9 kDa

    UniProt

    P01344

    途径

    Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation
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