IP6K1 Protein (His-GST)
This Recombinant IP6K1 protein is expressed in Baculovirus infected Insect Cells.
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产品编号 ABIN7196191
发货至:
中国
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Contact Info
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Quick Overview for IP6K1 Protein (His-GST) (ABIN7196191)
抗原
See all IP6K1 蛋白
IP6K1
(Inositol Hexakisphosphate Kinase 1 (IP6K1))
蛋白类型
Recombinant
宿主
人
资源
Baculovirus infected Insect Cells
纯度
> 85 % as determined by reducing SDS-PAGE.
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标记
- This IP6K1 protein is labelled with His-GST.
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原理
- Recombinant Human IHPK1 Protein (His & GST Tag)
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序列
- Met 1-Gln 441
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产品特性
- A DNA sequence encoding the human IHPK1 (Q92551-1) (Met1-Gln441) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Inositol Hexakisphosphate Kinase 1 (IP6K1) (AA 182-275) protein (GST tag)
IP6K1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Inositol Hexakisphosphate Kinase 1 (IP6K1) (AA 1-441) protein (His tag)IP6K1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- IP6K1 (Inositol Hexakisphosphate Kinase 1 (IP6K1))
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别名
- IHPK1
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背景
- IHPK1,PiUS,IHPK1 is a inositol hexaphosphate kinase (IHPK) protein which belongs to the inositol phosphokinase (IPK) family. IHPK proteins are likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). IHPK1 may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. During cell death, IHPK1 activity is enhanced, and intracellular InsP7 level is augmented. The distribution of IHPK1 or another predisposing gene affected by position effect of translocation may explain the T2DM phenotype at least in this family.
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分子量
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Calculated MW: 78.0 kDa
Observed MW: 88 kDa
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基因ID
- 9807
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UniProt
- Q92551
抗原
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