Quick Overview for IgG2a Fc protein (Fc Tag) (ABIN7321258)
抗原
蛋白类型
宿主
资源
纯度
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标记
- Fc Tag
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原理
- Recombinant Rat IgG2A Fc/Igg-2a Protein
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序列
- Val98-Lys322
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产品特性
- Recombinant Rat Immunoglobulin G2A Fc is produced by our Mammalian expression system and the target gene encoding Val98-Lys322 is expressed.
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内毒素水平
- <1.0 EU per μg as determined by LAL test.
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IgG2a Fc (AA 98-330) protein
宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, pH 8.5.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- IgG2a Fc
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别名
- IgG2A Fc/Igg-2a
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背景
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Background: Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains-two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78 % amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and CH3, which cause the diffrence in the interaction with complement, NK and mast cells, induction or inhibition by specific cytokines, and ability to cross the placenta.
Synonym: Ig gamma-2A chain C region, Igg-2a
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分子量
- 35.2 kDa
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UniProt
- P20760
抗原
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