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HOXB4 Protein (His tag)

HOXB4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7319405
发货至: 中国
  • 抗原 See all HOXB4 蛋白
    HOXB4 (Homeobox B4 (HOXB4))
    蛋白类型
    Recombinant
    宿主
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 5
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This HOXB4 protein is labelled with His tag.
    原理
    Recombinant Human HOXB4 Protein (His Tag)
    序列
    Met1-Leu251
    产品特性
    Recombinant Human Homeobox protein B4 is produced by our E.coli expression system and the target gene encoding Met1-Leu251 is expressed with a 6His tag at the N-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product HOXB4 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 4 mM HCl.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    HOXB4 (Homeobox B4 (HOXB4))
    别名
    HOXB4 (HOXB4 产品)
    别名
    HOX-2.6 Protein, HOX2 Protein, HOX2F Protein, Hox-2.6 Protein, Chox-Z Protein, hox2 Protein, hox2f Protein, hox-2.6 Protein, XHox-b4 Protein, HOX-B4 Protein, Z-17 Protein, ZF-13 Protein, hoxb4 Protein, zf13 Protein, Hoxb4 Protein, RGD1560113 Protein, HOXB4 Protein, FrHOXB-4 Protein, HoxB4a Protein, homeobox B4 Protein, homeobox B4 S homeolog Protein, homeobox B4a Protein, hox4 protein Protein, homeo box B4 Protein, hoxb4a protein Protein, HOXB4 Protein, Hoxb4 Protein, hoxb4 Protein, hoxb4.S Protein, hoxb4a Protein, hox4 Protein
    背景

    Background: Homeobox B4 (HOXB4) is encoded by the HOXB4 gene which is a member of the the class I homeobox (HOX) gene family and encodes a nuclear protein with a homeobox DNA-binding domain. These genes are master control regulators of developmental programs including embryonic and adult hematopoiesis. Multiple HOX genes, including HOXB4, are highly expressed in the hematopoietic stem cells (HSC) compartment. HOXB4 gene can act in opposite ways when expressed by different cells, promoting the proliferation of stem cells whilst activating the apoptotic pathway in some embryonic structures. The protein HOXB4, as a homeodomain transcription factor, has been shown to be an important regulator of stem cell renewal and hematopoiesis. Incellular or ectopic expression of HOXB4 expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.

    Synonym: Homeobox protein Hox-B4, Homeobox protein Hox-2.6, Homeobox protein Hox-2F, HOXB4, HOX2F

    分子量
    29.8 kDa
    UniProt
    P17483
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