HK3 Protein (His-GST)
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北京 101111
Quick Overview for HK3 Protein (His-GST) (ABIN7196087)
抗原
See all HK3 蛋白蛋白类型
宿主
资源
纯度
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标记
- This HK3 protein is labelled with His-GST.
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原理
- Recombinant Human Hexokinase-3/HK3 Protein (His & GST Tag)
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序列
- Met 1-Val 923
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产品特性
- A DNA sequence encoding the human HK3 (P52790) (Met 1-Val 923) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Hexokinase 3 (White Cell) (HK3) (AA 1-923) protein (GST tag)
HK3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Hexokinase 3 (White Cell) (HK3) (AA 1-61) protein (His-IF2DI Tag)HK3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Hexokinase 3 (White Cell) (HK3) protein (Myc-DYKDDDDK Tag)HK3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as sterile solution of 50 mM Tris, 100 mM NaCl, pH 7.4
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- HK3 (Hexokinase 3 (White Cell) (HK3))
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别名
- Hexokinase-3/HK3
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背景
- HKIII,HXK3,Hexokinase-3, also known as Hexokinase type III, HKIII and HK3, is a protein which belongs to thehexokinase family. Hexokinase-3 / HK3 is anenzymewhich in humans is encoded by theHK2gene. Hexokinases phosphorylate glucoseto produceglucose 6-phosphate, committing glucose to theglycolytic pathway. In mammalian tissues hexokinase exists as four isoenzymes encoded by distinct genes. These proteins are homologous and are organized in two homologous domains, with the exception of hexokinase type IV which has only one. This organization is believed to be the result of a duplication and tandem fusion event involving the gene encoding for the ancestral hexokinase. The gene encodes hexokinase-3. Similar to hexokinases-1 and hexokinases-2, thisallostericenzyme is inhibited by its product glucose 6-phosphate.
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分子量
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Calculated MW: 127 kDa
Observed MW: 115 kDa
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基因ID
- 3101
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UniProt
- P52790
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途径
- Carbohydrate Homeostasis, Warburg Effect
抗原
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